Can I use the small beads in large tires?

A: In most cases, yes. Before we had the large beads, everyone used the small beads in all tires, and it's success is evident. Later on, through countless tests and years of user feedback, we found that the larger beads had several distinct advantages.
With a few tire types, like the GoodYear Fortera tires, the inner liner pattern prevents the small beads from working.

In large tires though, the larger beads cope with excessive moisture and inner liner patterns much more effectively, which makes them ideal for large off road tires and tractor trailer styles.
In addition, the small beads should use the Filtered Valve Cores, while the large beads don't need them.